Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HECTD3E3 ubiquitin-protein ligase HECTD3. (861 aa)    
Predicted Functional Partners:
UBA52
Ubiquitin-60S ribosomal protein L40.
    
 0.827
UBB
Uncharacterized protein.
    
 0.773
ENSMMUP00000071311
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.766
TRIP12
Thyroid hormone receptor interactor 12.
   
 
 0.749
FAU
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
    
 0.703
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 
 0.691
EPRS1
Glutamyl-prolyl-tRNA synthetase.
   
   0.652
RPS27A
Uncharacterized protein.
    
 0.644
RPS27A-2
Ubiquitin-40S ribosomal protein S27a.
    
 0.644
ENSMMUP00000067421
Ubiquitin-like domain-containing protein.
    
 0.644
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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