Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
VOPP1Vesicular, overexpressed in cancer, prosurvival protein 1. (172 aa)    
Predicted Functional Partners:
GUCA1A
Guanylate cyclase activator 1A.
      
 0.898
LANCL2
LanC-like protein 2.
      
 0.854
SEC61G
Protein transport protein Sec61 subunit gamma.
      
 0.813
STK17A
Serine/threonine kinase 17a; Belongs to the protein kinase superfamily.
      
 0.685
CYYR1
Cysteine and tyrosine rich 1.
      
 0.665
PSMA2
Proteasome subunit alpha type.
      
 0.657
HECW1
E3 ubiquitin-protein ligase HECW1.
      
 0.646
TMEM207
Transmembrane protein 207.
      
 0.641
HYI
Putative hydroxypyruvate isomerase; Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde); Belongs to the hyi family.
   
  
 0.616
WWOX
WW domain containing oxidoreductase.
    
 
 0.614
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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