Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADGRG6Adhesion G protein-coupled receptor G6; Belongs to the G-protein coupled receptor 2 family. (1247 aa)    
Predicted Functional Partners:
BEX3
Uncharacterized protein.
      
 0.841
PLPPR1
Lipid phosphate phosphatase-related protein type 1.
    
 
 0.604
LOXL2
Lysyl oxidase-like protein 2.
    
 
 0.563
COL11A1
Collagen alpha-1(XI) chain isoform A preproprotein.
    
 
 0.523
SELL
L-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia; Belongs to the selectin/LECAM family.
    
 0.523
PPP1CA
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
      
 0.517
EGR4
Early growth response 4.
      
 0.497
NAALADL1
N-acetylated alpha-linked acidic dipeptidase like 1.
      
 0.482
MEIS1
Meis homeobox 1.
      
 0.481
GNB4
Guanine nucleotide-binding protein subunit beta-4.
    
   0.469
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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