Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPHKAPSPHK1 interactor, AKAP domain containing. (1721 aa)    
Predicted Functional Partners:
PPP3CB
Serine/threonine-protein phosphatase.
      
 0.730
YWHAH
DEP domain-containing protein.
      
 0.673
CDKL1
Cyclin dependent kinase like 1; Belongs to the protein kinase superfamily.
   
  
 0.589
C4BPB
Complement component 4 binding protein beta.
      
 0.586
PDCL2
Phosducin like 2.
      
 0.585
AKAP10
A-kinase anchor protein 10, mitochondrial.
      
 0.578
ZPBP
Zona pellucida binding protein.
      
 0.564
SPHK1
Sphingosine kinase 1.
    
 
 0.533
PLBD1
Phospholipase B-like; Putative phospholipase.
      
 0.526
PTBP2
Polypyrimidine tract-binding protein 2.
      
 0.523
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.