Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMC5Transmembrane channel-like protein. (1005 aa)    
Predicted Functional Partners:
KCNMB2
KcnmB2_inactiv domain-containing protein.
      
 0.665
KCNMB1
Calcium-activated potassium channel subunit beta-1.
      
 0.602
RASA1
RAS p21 protein activator 1.
    
 
 0.583
SPATS1
Spermatogenesis associated serine rich 1.
      
 0.579
SYNGR2
Synaptogyrin.
      
 0.578
SKIV2L
Ski2 like RNA helicase.
    
 0.574
KAT6B
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
 0.573
GRIA4
Glutamate ionotropic receptor AMPA type subunit 4.
     
 0.545
KNTC1
Kinetochore associated 1.
      
 0.540
AZIN2
Antizyme inhibitor 2; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
      
 0.539
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (16%) [HD]