Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
DIRAS3DIRAS family GTPase 3. (228 aa)    
Predicted Functional Partners:
AKR1C8P
Aldo-keto reductase family 1 member C8, pseudogene.
    
 
 0.798
LOC722496
Aldo_ket_red domain-containing protein.
    
 
 0.798
LRRC17
Leucine rich repeat containing 17.
    
 0.793
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
    
 0.788
MEST
Mesoderm specific transcript.
    
 
 0.764
LEUTX
Leucine twenty homeobox.
      
 0.753
RARRES2
Retinoic acid receptor responder protein 2.
      
 0.748
RAPGEF4
Rap guanine nucleotide exchange factor 4.
   
 0.728
NAA60
Uncharacterized protein.
   
  
 0.667
VENTX
VENT homeobox.
     
 0.639
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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