Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CYSLTR1Cysteinyl leukotriene receptor 1. (337 aa)    
Predicted Functional Partners:
CYSLTR2
Cysteinyl leukotriene receptor 2.
  
0.971
GNAQ
Guanine nucleotide-binding protein G(Q) subunit alpha.
    
 0.805
GNA11
Guanine nucleotide-binding protein subunit alpha-11.
    
 0.794
GNA14
G protein subunit alpha 14.
    
 0.794
GNA15
Uncharacterized protein.
    
 0.760
LTC4S
Leukotriene C4 synthase.
      
 0.667
UTS2B
Urotensin 2B.
     
 0.618
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
 0.587
NTS
Neurotensin/neuromedin N.
    
 0.567
GNG4
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
  0.561
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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