Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SHLD2FAM35_C domain-containing protein. (881 aa)    
Predicted Functional Partners:
MAD2L2
Mitotic arrest deficient 2 like 2.
    
 
 0.902
SHLD3
Shieldin complex subunit 3.
    
 
 0.755
RIF1
Replication timing regulatory factor 1.
    
 
 0.627
CTC1
CST telomere replication complex component 1.
      
 0.625
NSRP1
DUF2040 domain-containing protein.
      
 0.602
CAPSL
Calcyphosine like.
      
 0.602
MTREX
Mtr4 exosome RNA helicase.
   
  
 0.601
DTX3
Deltex E3 ubiquitin ligase 3.
   
  
 0.601
SHLD1
Shieldin complex subunit 1.
   
 
 0.576
TRAK2
Trafficking kinesin-binding protein 2.
      
 0.569
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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