Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
COPS6COP9 signalosome subunit 6. (394 aa)    
Predicted Functional Partners:
COPS5
COP9 signalosome complex subunit 5.
   
 0.999
GPS1
G protein pathway suppressor 1.
   
 0.999
COPS8
COP9 signalosome subunit 8.
   
 0.998
COPS3
COP9 signalosome complex subunit 3 isoform 1.
   
 0.998
COPS7A
COP9 signalosome complex subunit 7a.
   
 0.997
COPS4
COP9 signalosome subunit 4.
   
 0.995
COPS2
COP9 signalosome complex subunit 2 isoform 1.
   
 0.994
LOC699342
PCI domain-containing protein.
   
 0.994
COPS7B
COP9 signalosome subunit 7B.
   
 0.984
CUL4B
Cullin 4B; Belongs to the cullin family.
    
 0.965
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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