Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC694628Annexin. (363 aa)    
Predicted Functional Partners:
CASP3
Caspase 3; Belongs to the peptidase C14A family.
    
 
 0.561
CD9
Tetraspanin.
   
 
 0.533
DYSF
Dysferlin.
   
 0.513
CD63
Tetraspanin.
   
 
 0.506
C5H4orf45
Chromosome 5 C4orf45 homolog.
    
 
 0.468
CASP8
Caspase 8; Belongs to the peptidase C14A family.
   
 
 0.462
SRPX2
Sushi repeat containing protein X-linked 2.
      
 0.457
PPP2CB
Serine/threonine-protein phosphatase.
   
 
 0.454
BCL2
BCL2 apoptosis regulator.
   
  
 0.442
TSG101
ESCRT-I complex subunit TSG101.
   
 
 0.429
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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