SDC3 protein (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SDC3

Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (463 aa)

Predicted Functional Partners:

PTN

0.811

GDNF

0.733

SDC1

0.704

PSPN

0.704

NRTN

0.672

NDST2

0.632

GPC3

0.624

HS6ST1

0.624

GPC4

0.622

HS6ST2

0.622

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GDNF	NRTN	ENSMMUP00000024951	ENSMMUP00000065757	Glial cell derived neurotrophic factor.	Neurturin preproprotein.	0.648
GDNF	PSPN	ENSMMUP00000024951	ENSMMUP00000074305	Glial cell derived neurotrophic factor.	Persephin.	0.646
GDNF	PTN	ENSMMUP00000024951	ENSMMUP00000080883	Glial cell derived neurotrophic factor.	Uncharacterized protein.	0.453
GDNF	SDC3	ENSMMUP00000024951	ENSMMUP00000017778	Glial cell derived neurotrophic factor.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.733
GPC3	GPC4	ENSMMUP00000045159	ENSMMUP00000004602	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Glypican-4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.552
GPC3	HS6ST1	ENSMMUP00000045159	ENSMMUP00000077801	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.	0.610
GPC3	HS6ST2	ENSMMUP00000045159	ENSMMUP00000005614	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.	0.642
GPC3	NDST2	ENSMMUP00000045159	ENSMMUP00000030257	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2.	0.677
GPC3	SDC1	ENSMMUP00000045159	ENSMMUP00000063420	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.575
GPC3	SDC3	ENSMMUP00000045159	ENSMMUP00000017778	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.624
GPC4	GPC3	ENSMMUP00000004602	ENSMMUP00000045159	Glypican-4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.552
GPC4	HS6ST1	ENSMMUP00000004602	ENSMMUP00000077801	Glypican-4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.	0.603
GPC4	HS6ST2	ENSMMUP00000004602	ENSMMUP00000005614	Glypican-4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.	0.630
GPC4	NDST2	ENSMMUP00000004602	ENSMMUP00000030257	Glypican-4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2.	0.744
GPC4	SDC1	ENSMMUP00000004602	ENSMMUP00000063420	Glypican-4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.606
GPC4	SDC3	ENSMMUP00000004602	ENSMMUP00000017778	Glypican-4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.622
HS6ST1	GPC3	ENSMMUP00000077801	ENSMMUP00000045159	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.610
HS6ST1	GPC4	ENSMMUP00000077801	ENSMMUP00000004602	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.	Glypican-4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.603
HS6ST1	NDST2	ENSMMUP00000077801	ENSMMUP00000030257	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2.	0.711
HS6ST1	SDC1	ENSMMUP00000077801	ENSMMUP00000063420	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.545