Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MS4A6AMembrane spanning 4-domains A6A. (248 aa)    
Predicted Functional Partners:
MS4A18
Membrane spanning 4-domains A18.
      
 0.727
CD2AP
CD2-associated protein.
   
  
 0.696
ABCA7
ATP binding cassette subfamily A member 7.
      
 0.672
PICALM
Phosphatidylinositol binding clathrin assembly protein.
   
  
 0.665
AIF1
Allograft inflammatory factor 1; Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation (By similarity).
   
  
 0.655
BIN1
Bridging integrator 1.
      
 0.632
EPHA1
EPH receptor A1.
      
 0.616
CD33
CD33 molecule.
   
  
 0.615
MS4A15
Membrane spanning 4-domains A15.
   
  
0.576
MS4A4A
Uncharacterized protein.
  
  
0.572
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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