Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IPO5Importin 5. (1097 aa)    
Predicted Functional Partners:
KPNB1
Karyopherin subunit beta 1.
   
 
 0.967
IPO7
Importin-7.
   
 
 0.958
CSE1L
Importin N-terminal domain-containing protein.
   
 
 0.926
IPO4
Importin 4.
   
 
0.915
TNPO1
Transportin-1 isoform 1.
   
 
0.913
RAN
GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.
   
 
 0.908
XPO1
Exportin-1.
   
 
 0.893
DDX56
DEAD-box helicase 56.
   
 
 0.856
IPO11
Importin 11.
   
  
 0.836
NUP98
Nucleoporin 98.
   
 
 0.831
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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