Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
TMEM259Transmembrane protein 259. (598 aa)    
Predicted Functional Partners:
TMUB1
Transmembrane and ubiquitin-like domain-containing protein 1 isoform 1.
    
 
 0.779
RNF5
E3 ubiquitin-protein ligase RNF5.
    
 
 0.776
TMUB2
Ubiquitin-like domain-containing protein.
    
 
 0.731
CACHD1
Cache domain containing 1.
      
 0.672
C4H6orf120
Chromosome 4 C6orf120 homolog.
      
 0.651
STT3A
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A.
      
 0.642
GGCX
Vitamin K-dependent gamma-carboxylase isoform 1.
      
 0.629
SMPDL3B
Uncharacterized protein.
      
 0.620
EMC1
ER membrane protein complex subunit 1.
      
 0.609
NSFL1C
Uncharacterized protein.
      
 0.580
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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