Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCDC27Coiled-coil domain containing 27. (652 aa)    
Predicted Functional Partners:
CC2D1B
Coiled-coil and C2 domain containing 1B.
    
   0.902
MYLK
Myosin light chain kinase.
    
   0.902
TP73
Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
      
 0.771
CC2D1A
Coiled-coil and C2 domain containing 1A.
    
   0.677
DNAJC5
DnaJ homolog subfamily C member 5.
      
 0.610
KCTD10
Potassium channel tetramerization domain containing 10.
      
 0.604
TRIP11
Thyroid hormone receptor interactor 11.
      
 0.591
TTN
Titin.
    
   0.582
SPEGNB
SPEG neighbor.
    
   0.582
C9H10orf120
Chromosome 9 C10orf120 homolog.
      
 0.526
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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