Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
VPS45Vacuolar protein sorting-associated protein 45; Belongs to the STXBP/unc-18/SEC1 family. (570 aa)    
Predicted Functional Partners:
RBSN
Rabenosyn, RAB effector.
    
 0.998
STX16
Syntaxin-16 isoform a; Belongs to the syntaxin family.
    
 
 0.945
VTI1A
t-SNARE coiled-coil homology domain-containing protein.
   
 
 0.907
MTO1
Mitochondrial tRNA translation optimization 1.
 
      0.900
ERGIC3
ERGIC and golgi 3.
 
      0.900
COG4
Conserved oligomeric Golgi complex subunit 4 isoform 1.
   
 
 0.884
STX6
Syntaxin-6; Belongs to the syntaxin family.
    
 
 0.882
COG6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
    
 0.878
VPS18
Vacuolar protein sorting-associated protein 18-like protein.
    
 0.878
VPS33A
Vacuolar protein sorting-associated protein 33A; Belongs to the STXBP/unc-18/SEC1 family.
   
 0.849
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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