Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PNRC2Proline rich nuclear receptor coactivator 2. (139 aa)    
Predicted Functional Partners:
DCP1A
mRNA-decapping enzyme 1A.
    
 0.968
DCP2
mRNA-decapping enzyme 2 isoform 1.
    
 
 0.819
SMG8
Protein SMG8.
     
 0.774
UPF1
UPF1 RNA helicase and ATPase.
    
 0.741
DCP1B
Decapping mRNA 1B.
    
 0.736
ESRRG
Estrogen related receptor gamma.
    
 
 0.705
SMG9
Uncharacterized protein.
     
 0.693
FUCA1
Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
      
 0.663
SMG5
SMG5 nonsense mediated mRNA decay factor.
     
 0.633
EDC3
Enhancer of mRNA-decapping protein 3.
    
 
 0.620
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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