PTPN7 protein (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

PTPN7

Protein tyrosine phosphatase non-receptor type 7. (360 aa)

Predicted Functional Partners:

MAPK1

0.994

MAPK3

0.989

MAPK14

0.978

MAPK11

0.962

MAPK13

0.949

PTPN5

0.937

DUSP3

0.931

MAPK10

0.917

MAPK9

0.908

PTPRR

0.901

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DUSP3	MAPK1	ENSMMUP00000075981	ENSMMUP00000016444	Tyrosine-protein phosphatase domain-containing protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.979
DUSP3	MAPK10	ENSMMUP00000075981	ENSMMUP00000042171	Tyrosine-protein phosphatase domain-containing protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.938
DUSP3	MAPK11	ENSMMUP00000075981	ENSMMUP00000018541	Tyrosine-protein phosphatase domain-containing protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.936
DUSP3	MAPK13	ENSMMUP00000075981	ENSMMUP00000045645	Tyrosine-protein phosphatase domain-containing protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.936
DUSP3	MAPK14	ENSMMUP00000075981	ENSMMUP00000011075	Tyrosine-protein phosphatase domain-containing protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.936
DUSP3	MAPK3	ENSMMUP00000075981	ENSMMUP00000053373	Tyrosine-protein phosphatase domain-containing protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.981
DUSP3	MAPK9	ENSMMUP00000075981	ENSMMUP00000002308	Tyrosine-protein phosphatase domain-containing protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.952
DUSP3	PTPN5	ENSMMUP00000075981	ENSMMUP00000009343	Tyrosine-protein phosphatase domain-containing protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Tyrosine-protein phosphatase domain-containing protein.	0.928
DUSP3	PTPN7	ENSMMUP00000075981	ENSMMUP00000018133	Tyrosine-protein phosphatase domain-containing protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Protein tyrosine phosphatase non-receptor type 7.	0.931
DUSP3	PTPRR	ENSMMUP00000075981	ENSMMUP00000039166	Tyrosine-protein phosphatase domain-containing protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Protein tyrosine phosphatase receptor type R.	0.928
MAPK1	DUSP3	ENSMMUP00000016444	ENSMMUP00000075981	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Tyrosine-protein phosphatase domain-containing protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.979
MAPK1	MAPK11	ENSMMUP00000016444	ENSMMUP00000018541	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.959
MAPK1	MAPK13	ENSMMUP00000016444	ENSMMUP00000045645	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.943
MAPK1	MAPK14	ENSMMUP00000016444	ENSMMUP00000011075	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.993
MAPK1	MAPK3	ENSMMUP00000016444	ENSMMUP00000053373	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.999
MAPK1	PTPN5	ENSMMUP00000016444	ENSMMUP00000009343	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Tyrosine-protein phosphatase domain-containing protein.	0.965
MAPK1	PTPN7	ENSMMUP00000016444	ENSMMUP00000018133	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein tyrosine phosphatase non-receptor type 7.	0.994
MAPK1	PTPRR	ENSMMUP00000016444	ENSMMUP00000039166	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein tyrosine phosphatase receptor type R.	0.993
MAPK10	DUSP3	ENSMMUP00000042171	ENSMMUP00000075981	Mitogen-activated protein kinase.	Tyrosine-protein phosphatase domain-containing protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.938
MAPK10	MAPK11	ENSMMUP00000042171	ENSMMUP00000018541	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.937