Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADGBCalpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (1667 aa)    
Predicted Functional Partners:
IQCA1
IQ motif containing with AAA domain 1.
   
 
 0.686
CYGB
GLOBIN domain-containing protein; Belongs to the globin family.
   
 
 0.686
MB
Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
   
 
 0.679
CCDC149
Coiled-coil domain containing 149.
      
 0.672
SLC36A1
Solute carrier family 36 member 1.
   
  
 0.670
ULK4
Unc-51 like kinase 4.
      
 0.649
NGB
Neuroglobin; Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes (By similarity).
   
 
 0.645
MUC13
Mucin 13, cell surface associated.
    
 0.615
IQCA1L
IQ motif containing with AAA domain 1 like.
   
 
 0.536
PCDH15
Protocadherin related 15.
      
 0.532
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.