Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ERN2Endoplasmic reticulum to nucleus signaling 2. (867 aa)    
Predicted Functional Partners:
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.958
HSPA5
78 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family.
    
 0.917
ERN1
Endoplasmic reticulum to nucleus signaling 1.
  
  
0.904
UBFD1
Ubiquitin family domain containing 1.
 
  
 0.881
DCTN5
Dynactin subunit 5 isoform 1.
      
 0.792
AGR2
Uncharacterized protein.
   
 
 0.778
ATF6B
Activating transcription factor 6 beta.
    
 0.729
XBP1
X-box binding protein 1.
    
 0.724
EARS2
Glutamyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
    
 0.705
ANKRD45
ANK_REP_REGION domain-containing protein.
    
 0.679
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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