Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PARP8Poly [ADP-ribose] polymerase. (894 aa)    
Predicted Functional Partners:
AK6
Uncharacterized protein.
      
 0.766
TPI1
Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.
  
 
 0.753
LOC694593
Uncharacterized protein.
  
 0.731
ENO3
Enolase 3.
  
 0.731
ENO2
Gamma-enolase.
  
 0.731
ENO1
Uncharacterized protein.
  
 0.731
ENO4
Enolase 4.
  
 0.723
RPS3
40S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
  
 
 0.707
PGK2
Phosphoglycerate kinase.
  
 0.694
LOC704249
Phosphoglycerate kinase.
  
 0.694
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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