Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NMUR2Neuromedin U receptor 2; Belongs to the G-protein coupled receptor 1 family. (414 aa)    
Predicted Functional Partners:
NMU
Neuromedin U.
    
 0.999
NMS
Neuromedin S.
    
 0.998
NMUR1
Neuromedin U receptor 1; Belongs to the G-protein coupled receptor 1 family.
  
  
0.938
NTS
Neurotensin/neuromedin N.
    
 0.709
GRP
Gastrin releasing peptide.
    
 0.669
CCK
Cholecystokinin preproprotein.
    
 0.664
MECP2
Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
     
 0.662
IL1B
Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.
      
 0.656
NPS
Neuropeptide S.
     
 0.632
UTS2
Urotensin-2; Highly potent vasoconstrictor; Belongs to the urotensin-2 family.
   
 
 0.624
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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