Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
P2RY4Uncharacterized protein; Belongs to the G-protein coupled receptor 1 family. (365 aa)    
Predicted Functional Partners:
GNA11
Guanine nucleotide-binding protein subunit alpha-11.
    
 0.928
GNAQ
Guanine nucleotide-binding protein G(Q) subunit alpha.
    
 0.928
SFTPC
Pulmonary surfactant-associated protein C; Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.
     
  0.654
SFTPB
Surfactant protein B.
     
  0.603
F7B371_MACMU
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
     
  0.486
PDPK1
3-phosphoinositide dependent protein kinase 1.
     
  0.486
GNG4
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
  0.468
GNB4
Guanine nucleotide-binding protein subunit beta-4.
    
  0.464
GNB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.
    
  0.464
GNB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2.
    
  0.464
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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