Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PDZD11PDZ domain-containing protein. (180 aa)    
Predicted Functional Partners:
SLC5A6
Sodium-dependent multivitamin transporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
    
 0.946
ATP7A
ATPase copper transporting alpha.
    
 0.895
PLEKHA5
Pleckstrin homology domain containing A5.
    
 0.868
ATP7B
ATPase copper transporting beta.
    
 0.813
ATOX1
Copper transport protein ATOX1.
     
 0.779
PLEKHA7
Pleckstrin homology domain containing A7.
    
 0.653
TSPAN33
Tetraspanin.
    
 0.608
MED31
Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.579
STXBP2
Syntaxin binding protein 2; Belongs to the STXBP/unc-18/SEC1 family.
     
 0.538
SYTL4
Synaptotagmin-like protein 4.
     
 0.529
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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