Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TCAF2Peptidase M60 domain-containing protein. (919 aa)    
Predicted Functional Partners:
SPAG4
Sperm associated antigen 4.
      
 0.666
TRPM8
Transient receptor potential cation channel subfamily M member 8.
      
 0.665
IGLON5
Uncharacterized protein.
      
 0.608
PFKFB4
6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 4.
      
 0.601
PTPN20
Protein tyrosine phosphatase non-receptor type 20.
      
 0.538
DUSP22
Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
      
 0.529
ARHGEF5
Rho guanine nucleotide exchange factor 5.
      
 0.489
BNIP3L
BCL2 interacting protein 3 like.
      
 0.480
CD8B
Ig-like domain-containing protein.
      
 0.477
NAIP
NLR family apoptosis inhibitory protein.
      
 0.464
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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