NR5A1 protein (Macaca mulatta) - STRING interaction network

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Score

NR5A1

Nuclear receptor subfamily 5 group A member 1. (500 aa)

Predicted Functional Partners:

NR0B1

0.998

SOX9

0.939

PRKACA

0.918

PRKACB

0.918

LSM1

0.916

PRKACG

0.916

WT1

0.895

NCOA2

0.873

AMH

0.870

NR0B2

0.846

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMH	LSM1	ENSMMUP00000071412	ENSMMUP00000017990	Anti-Mullerian hormone.	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.	0.628
AMH	NR0B1	ENSMMUP00000071412	ENSMMUP00000016782	Anti-Mullerian hormone.	Nuclear receptor subfamily 0 group B member 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity). Belongs to the nuclear hormone receptor family. NR0 subfamily.	0.656
AMH	NR5A1	ENSMMUP00000071412	ENSMMUP00000018545	Anti-Mullerian hormone.	Nuclear receptor subfamily 5 group A member 1.	0.870
AMH	SOX9	ENSMMUP00000071412	ENSMMUP00000073101	Anti-Mullerian hormone.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.775
AMH	WT1	ENSMMUP00000071412	ENSMMUP00000012938	Anti-Mullerian hormone.	WT1 transcription factor.	0.615
LSM1	AMH	ENSMMUP00000017990	ENSMMUP00000071412	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.	Anti-Mullerian hormone.	0.628
LSM1	NR0B1	ENSMMUP00000017990	ENSMMUP00000016782	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.	Nuclear receptor subfamily 0 group B member 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity). Belongs to the nuclear hormone receptor family. NR0 subfamily.	0.750
LSM1	NR5A1	ENSMMUP00000017990	ENSMMUP00000018545	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.	Nuclear receptor subfamily 5 group A member 1.	0.916
LSM1	PRKACA	ENSMMUP00000017990	ENSMMUP00000054168	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.539
LSM1	PRKACB	ENSMMUP00000017990	ENSMMUP00000059748	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.	cAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily.	0.539
LSM1	PRKACG	ENSMMUP00000017990	ENSMMUP00000026815	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.	cAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.	0.539
NCOA2	NR5A1	ENSMMUP00000021016	ENSMMUP00000018545	Nuclear receptor coactivator.	Nuclear receptor subfamily 5 group A member 1.	0.873
NR0B1	AMH	ENSMMUP00000016782	ENSMMUP00000071412	Nuclear receptor subfamily 0 group B member 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity). Belongs to the nuclear hormone receptor family. NR0 subfamily.	Anti-Mullerian hormone.	0.656
NR0B1	LSM1	ENSMMUP00000016782	ENSMMUP00000017990	Nuclear receptor subfamily 0 group B member 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity). Belongs to the nuclear hormone receptor family. NR0 subfamily.	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.	0.750
NR0B1	NR5A1	ENSMMUP00000016782	ENSMMUP00000018545	Nuclear receptor subfamily 0 group B member 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity). Belongs to the nuclear hormone receptor family. NR0 subfamily.	Nuclear receptor subfamily 5 group A member 1.	0.998
NR0B1	SOX9	ENSMMUP00000016782	ENSMMUP00000073101	Nuclear receptor subfamily 0 group B member 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity). Belongs to the nuclear hormone receptor family. NR0 subfamily.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.579
NR0B1	WT1	ENSMMUP00000016782	ENSMMUP00000012938	Nuclear receptor subfamily 0 group B member 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity). Belongs to the nuclear hormone receptor family. NR0 subfamily.	WT1 transcription factor.	0.687
NR0B2	NR5A1	ENSMMUP00000013473	ENSMMUP00000018545	Nuclear receptor subfamily 0 group B member 2.	Nuclear receptor subfamily 5 group A member 1.	0.846
NR5A1	AMH	ENSMMUP00000018545	ENSMMUP00000071412	Nuclear receptor subfamily 5 group A member 1.	Anti-Mullerian hormone.	0.870
NR5A1	LSM1	ENSMMUP00000018545	ENSMMUP00000017990	Nuclear receptor subfamily 5 group A member 1.	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.	0.916