Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
WDR5WD repeat domain 5. (426 aa)    
Predicted Functional Partners:
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit.
   
 0.999
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
   
0.999
KMT2A
Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
   
 0.996
KMT2D
Lysine methyltransferase 2D.
   
 0.994
DPY30
Dpy-30 histone methyltransferase complex regulatory subunit.
   
 0.993
MEN1
Menin isoform 2.
    
 0.988
SETD1A
Uncharacterized protein.
    
 0.988
KANSL1
KAT8 regulatory NSL complex subunit 1.
    
 0.987
NCOA6
Nuclear receptor coactivator 6.
    
 0.986
SETD1B
SET domain containing 1B, histone lysine methyltransferase.
    
 0.983
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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