Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ESRRGEstrogen related receptor gamma. (470 aa)    
Predicted Functional Partners:
PPARGC1A
PPARG coactivator 1 alpha.
   
 0.959
ESRRA
Estrogen related receptor alpha.
    
   0.902
PPARGC1B
PPARG coactivator 1 beta.
    
 0.899
NR0B2
Nuclear receptor subfamily 0 group B member 2.
    
 0.829
NCOA1
Nuclear receptor coactivator.
    
 0.821
NRIP1
Nuclear receptor interacting protein 1.
    
 0.810
NR0B1
Nuclear receptor subfamily 0 group B member 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity). Belongs to the nuclear hormone receptor family. NR0 subfamily.
    
 0.807
NCOR2
Nuclear receptor corepressor 2.
    
 0.799
ESRRB
Estrogen related receptor beta.
    
 
 0.745
PNRC2
Proline rich nuclear receptor coactivator 2.
    
 
 0.705
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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