Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (517 aa)    
Predicted Functional Partners:
RAMP2
Receptor activity-modifying protein 2.
   
 0.999
RAMP3
Uncharacterized protein.
   
 0.999
RAMP1
Uncharacterized protein.
    
 0.997
ADM
Adrenomedullin.
    
 0.992
IAPP
Islet amyloid polypeptide.
     
 0.989
CALCA
Calcitonin related polypeptide alpha.
   
 0.989
CALCB
Calcitonin related polypeptide beta.
     
 0.980
GNB4
Guanine nucleotide-binding protein subunit beta-4.
    
  0.976
GNB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.
    
  0.976
GNG4
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
  0.973
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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