Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (490 aa)    
Predicted Functional Partners:
ARRB2
Arrestin beta 2.
   
 0.989
SLC6A3
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
   
 0.986
GNB4
Guanine nucleotide-binding protein subunit beta-4.
    
  0.973
GNB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.
    
  0.973
GNAI3
Guanine nucleotide-binding protein G(K) subunit alpha.
    
 0.972
GNAI1
G protein subunit alpha i1.
    
 0.972
ARRB1
Arrestin beta 1.
   
 0.972
DRD4
Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.
    
0.971
DRD3
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
  
 
0.971
GNAO1
Guanine nucleotide-binding protein G(O) subunit alpha isoform a.
   
 0.969
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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