Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF19Rho guanine nucleotide exchange factor 19. (809 aa)    
Predicted Functional Partners:
RHOA
Ras homolog family member A.
    
 0.773
KIAA1109
KIAA1109.
      
 0.769
ALS2CL
ALS2 C-terminal like.
      
 0.696
PLEKHG4B
Pleckstrin homology and RhoGEF domain containing G4B.
     
 0.682
ARHGEF33
Rho guanine nucleotide exchange factor 33.
    
 0.672
ZMIZ2
Zinc finger MIZ domain-containing protein 2 isoform 1.
      
 0.663
ARHGEF38
Rho guanine nucleotide exchange factor 38.
     
 0.647
MAB21L3
Mab-21 like 3.
   
  
 0.628
KALRN
Uncharacterized protein.
     
 0.628
ARHGEF9
Cdc42 guanine nucleotide exchange factor 9.
     
 0.589
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (10%) [HD]