node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHRNA10 | OTOR | ENSMMUP00000005269 | ENSMMUP00000019030 | Cholinergic receptor nicotinic alpha 10 subunit. | Otoraplin. | 0.644 |
CHRNA10 | OTUD6A | ENSMMUP00000005269 | ENSMMUP00000079662 | Cholinergic receptor nicotinic alpha 10 subunit. | DUBA-2. | 0.422 |
CHRNA10 | SNX3 | ENSMMUP00000005269 | ENSMMUP00000026798 | Cholinergic receptor nicotinic alpha 10 subunit. | Sorting nexin-3 isoform a. | 0.680 |
ELOVL3 | HACD2 | ENSMMUP00000029959 | ENSMMUP00000071849 | Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.496 |
ELOVL3 | OTOR | ENSMMUP00000029959 | ENSMMUP00000019030 | Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] | Otoraplin. | 0.483 |
ELOVL3 | SLC46A2 | ENSMMUP00000029959 | ENSMMUP00000000763 | Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] | Solute carrier family 46 member 2. | 0.414 |
GAPT | OTOR | ENSMMUP00000069272 | ENSMMUP00000019030 | Uncharacterized protein. | Otoraplin. | 0.454 |
GAPT | OTUD6A | ENSMMUP00000069272 | ENSMMUP00000079662 | Uncharacterized protein. | DUBA-2. | 0.580 |
GAPT | SNX3 | ENSMMUP00000069272 | ENSMMUP00000026798 | Uncharacterized protein. | Sorting nexin-3 isoform a. | 0.472 |
HACD2 | ELOVL3 | ENSMMUP00000071849 | ENSMMUP00000029959 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] | 0.496 |
HACD2 | OTOR | ENSMMUP00000071849 | ENSMMUP00000019030 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Otoraplin. | 0.748 |
HACD2 | SLC38A4 | ENSMMUP00000071849 | ENSMMUP00000016185 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Na(+)-coupled neutral amino acid transporter 4. | 0.540 |
HACD2 | SLC46A2 | ENSMMUP00000071849 | ENSMMUP00000000763 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Solute carrier family 46 member 2. | 0.640 |
HACD2 | SLC7A8 | ENSMMUP00000071849 | ENSMMUP00000025824 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Large neutral amino acids transporter small subunit 2 isoform a. | 0.591 |
OTOR | CHRNA10 | ENSMMUP00000019030 | ENSMMUP00000005269 | Otoraplin. | Cholinergic receptor nicotinic alpha 10 subunit. | 0.644 |
OTOR | ELOVL3 | ENSMMUP00000019030 | ENSMMUP00000029959 | Otoraplin. | Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] | 0.483 |
OTOR | GAPT | ENSMMUP00000019030 | ENSMMUP00000069272 | Otoraplin. | Uncharacterized protein. | 0.454 |
OTOR | HACD2 | ENSMMUP00000019030 | ENSMMUP00000071849 | Otoraplin. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.748 |
OTOR | OTUD6A | ENSMMUP00000019030 | ENSMMUP00000079662 | Otoraplin. | DUBA-2. | 0.581 |
OTOR | SLC38A4 | ENSMMUP00000019030 | ENSMMUP00000016185 | Otoraplin. | Na(+)-coupled neutral amino acid transporter 4. | 0.539 |