STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRPF19Pre-mRNA processing factor 19. (512 aa)    
Predicted Functional Partners:
BCAS2
Pre-mRNA-splicing factor SPF27.
   
 0.998
PLRG1
Pleiotropic regulator 1 isoform 1.
   
0.998
XAB2
Pre-mRNA-splicing factor SYF1.
   
 0.998
CDC5L
Cell division cycle 5-like protein.
   
 0.997
CRNKL1
Crooked neck pre-mRNA splicing factor 1.
   
 0.996
ISY1
Uncharacterized protein.
    
 0.995
PPIE
Peptidylprolyl isomerase E.
   
 0.995
AQR
RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
    
 0.995
CWC15
Protein CWC15 homolog.
    
 0.992
CWC22
CWC22 spliceosome associated protein homolog.
   
 0.990
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.