Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PARD3BPar-3 family cell polarity regulator beta. (1204 aa)    
Predicted Functional Partners:
PARD6B
Partitioning defective 6 homolog beta.
   
 0.872
PRKCZ
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    
 0.835
PRKCI
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    
 0.835
PARD6G
Par-6 family cell polarity regulator gamma.
   
 0.807
LLGL1
LLGL scribble cell polarity complex component 1.
    
 
 0.804
PARD6A
Par-6 family cell polarity regulator alpha.
   
 0.775
INSC
INSC spindle orientation adaptor protein.
    
 
 0.723
MPP5
Membrane palmitoylated protein 5; Belongs to the MAGUK family.
   
 0.634
ANKLE2
Ankyrin repeat and LEM domain containing 2.
    
 
 0.620
VRK1
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 
 0.593
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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