ZIC5 protein (Macaca mulatta) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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co-expression

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[Homology]

Score

ZIC5

Zic family member 5. (657 aa)

Predicted Functional Partners:

ZIC3

0.911

ZIC1

0.854

ZIC2

0.651

TLX3

0.567

PAX5

0.554

CELF6

0.535

POU5F1

0.524

LHFPL4

0.487

SOX15

0.484

AKAP8L

0.466

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKAP8L	ZIC5	ENSMMUP00000031778	ENSMMUP00000019456	Uncharacterized protein; Belongs to the AKAP95 family.	Zic family member 5.	0.466
CELF6	LHFPL4	ENSMMUP00000074192	ENSMMUP00000073645	CUGBP Elav-like family member 6 isoform 1.	Uncharacterized protein.	0.773
CELF6	ZIC2	ENSMMUP00000074192	ENSMMUP00000019457	CUGBP Elav-like family member 6 isoform 1.	Zic family member 2.	0.408
CELF6	ZIC5	ENSMMUP00000074192	ENSMMUP00000019456	CUGBP Elav-like family member 6 isoform 1.	Zic family member 5.	0.535
LHFPL4	CELF6	ENSMMUP00000073645	ENSMMUP00000074192	Uncharacterized protein.	CUGBP Elav-like family member 6 isoform 1.	0.773
LHFPL4	TLX3	ENSMMUP00000073645	ENSMMUP00000075950	Uncharacterized protein.	T cell leukemia homeobox 3.	0.619
LHFPL4	ZIC1	ENSMMUP00000073645	ENSMMUP00000006304	Uncharacterized protein.	Zic family member 1.	0.404
LHFPL4	ZIC5	ENSMMUP00000073645	ENSMMUP00000019456	Uncharacterized protein.	Zic family member 5.	0.487
PAX5	ZIC1	ENSMMUP00000043020	ENSMMUP00000006304	Paired box 5.	Zic family member 1.	0.601
PAX5	ZIC2	ENSMMUP00000043020	ENSMMUP00000019457	Paired box 5.	Zic family member 2.	0.524
PAX5	ZIC5	ENSMMUP00000043020	ENSMMUP00000019456	Paired box 5.	Zic family member 5.	0.554
POU5F1	SOX15	ENSMMUP00000020597	ENSMMUP00000077836	POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency; Belongs to the POU transcription factor family. Class-5 subfamily.	SRY-box transcription factor 15.	0.856
POU5F1	ZIC1	ENSMMUP00000020597	ENSMMUP00000006304	POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency; Belongs to the POU transcription factor family. Class-5 subfamily.	Zic family member 1.	0.570
POU5F1	ZIC2	ENSMMUP00000020597	ENSMMUP00000019457	POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency; Belongs to the POU transcription factor family. Class-5 subfamily.	Zic family member 2.	0.644
POU5F1	ZIC3	ENSMMUP00000020597	ENSMMUP00000022867	POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency; Belongs to the POU transcription factor family. Class-5 subfamily.	Zic family member 3.	0.684
POU5F1	ZIC5	ENSMMUP00000020597	ENSMMUP00000019456	POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency; Belongs to the POU transcription factor family. Class-5 subfamily.	Zic family member 5.	0.524
SOX15	POU5F1	ENSMMUP00000077836	ENSMMUP00000020597	SRY-box transcription factor 15.	POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency; Belongs to the POU transcription factor family. Class-5 subfamily.	0.856
SOX15	ZIC5	ENSMMUP00000077836	ENSMMUP00000019456	SRY-box transcription factor 15.	Zic family member 5.	0.484
TLX3	LHFPL4	ENSMMUP00000075950	ENSMMUP00000073645	T cell leukemia homeobox 3.	Uncharacterized protein.	0.619
TLX3	ZIC2	ENSMMUP00000075950	ENSMMUP00000019457	T cell leukemia homeobox 3.	Zic family member 2.	0.531