| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACE | CYP11B2 | ENSMMUP00000056909 | ENSMMUP00000001289 | Angiotensin-converting enzyme. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.408 |
| ACE | NR3C2 | ENSMMUP00000056909 | ENSMMUP00000080316 | Angiotensin-converting enzyme. | Nuclear receptor subfamily 3 group C member 2. | 0.784 |
| ACE | REN | ENSMMUP00000056909 | ENSMMUP00000011105 | Angiotensin-converting enzyme. | Renin; Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. | 0.995 |
| CRHR1 | FKBP5 | ENSMMUP00000055825 | ENSMMUP00000015121 | Corticotropin-releasing factor receptor 1; G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to st [...] | Peptidylprolyl isomerase. | 0.677 |
| CRHR1 | NR3C1 | ENSMMUP00000055825 | ENSMMUP00000000567 | Corticotropin-releasing factor receptor 1; G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to st [...] | Nuclear receptor subfamily 3 group C member 1. | 0.728 |
| CRHR1 | NR3C2 | ENSMMUP00000055825 | ENSMMUP00000080316 | Corticotropin-releasing factor receptor 1; G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to st [...] | Nuclear receptor subfamily 3 group C member 2. | 0.768 |
| CYP11B2 | ACE | ENSMMUP00000001289 | ENSMMUP00000056909 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Angiotensin-converting enzyme. | 0.408 |
| CYP11B2 | HSD11B2 | ENSMMUP00000001289 | ENSMMUP00000010536 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Hydroxysteroid 11-beta dehydrogenase 2. | 0.960 |
| CYP11B2 | NR3C2 | ENSMMUP00000001289 | ENSMMUP00000080316 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Nuclear receptor subfamily 3 group C member 2. | 0.739 |
| CYP11B2 | REN | ENSMMUP00000001289 | ENSMMUP00000011105 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Renin; Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. | 0.561 |
| FKBP4 | FKBP5 | ENSMMUP00000009718 | ENSMMUP00000015121 | Peptidylprolyl isomerase. | Peptidylprolyl isomerase. | 0.994 |
| FKBP4 | NR3C1 | ENSMMUP00000009718 | ENSMMUP00000000567 | Peptidylprolyl isomerase. | Nuclear receptor subfamily 3 group C member 1. | 0.989 |
| FKBP4 | NR3C2 | ENSMMUP00000009718 | ENSMMUP00000080316 | Peptidylprolyl isomerase. | Nuclear receptor subfamily 3 group C member 2. | 0.861 |
| FKBP4 | PGR | ENSMMUP00000009718 | ENSMMUP00000015545 | Peptidylprolyl isomerase. | Uncharacterized protein. | 0.965 |
| FKBP5 | CRHR1 | ENSMMUP00000015121 | ENSMMUP00000055825 | Peptidylprolyl isomerase. | Corticotropin-releasing factor receptor 1; G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to st [...] | 0.677 |
| FKBP5 | FKBP4 | ENSMMUP00000015121 | ENSMMUP00000009718 | Peptidylprolyl isomerase. | Peptidylprolyl isomerase. | 0.994 |
| FKBP5 | HSD11B2 | ENSMMUP00000015121 | ENSMMUP00000010536 | Peptidylprolyl isomerase. | Hydroxysteroid 11-beta dehydrogenase 2. | 0.445 |
| FKBP5 | NR3C1 | ENSMMUP00000015121 | ENSMMUP00000000567 | Peptidylprolyl isomerase. | Nuclear receptor subfamily 3 group C member 1. | 0.990 |
| FKBP5 | NR3C2 | ENSMMUP00000015121 | ENSMMUP00000080316 | Peptidylprolyl isomerase. | Nuclear receptor subfamily 3 group C member 2. | 0.927 |
| FKBP5 | PGR | ENSMMUP00000015121 | ENSMMUP00000015545 | Peptidylprolyl isomerase. | Uncharacterized protein. | 0.935 |
