STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NR3C2Nuclear receptor subfamily 3 group C member 2. (984 aa)    
Predicted Functional Partners:
NR3C1
Nuclear receptor subfamily 3 group C member 1.
  
 
0.857
NCOA1
Nuclear receptor coactivator.
    
 0.853
FKBP5
Peptidylprolyl isomerase.
   
 0.842
NDST4
N-deacetylase and N-sulfotransferase 4.
      
 0.807
REN
Renin; Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
    
 
 0.789
PGR
Uncharacterized protein.
     
0.776
FKBP4
Peptidylprolyl isomerase.
   
 0.772
ASTN2
Astrotactin 2.
    
 
 0.768
ACE
Angiotensin-converting enzyme.
      
 0.756
KCNQ5
Potassium voltage-gated channel subfamily Q member 5.
      
 0.751
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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