Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
KRT4Keratin 4; Belongs to the intermediate filament family. (520 aa)    
Predicted Functional Partners:
KRT13
IF rod domain-containing protein; Belongs to the intermediate filament family.
  
0.970
ANKRD65
Ankyrin repeat domain 65.
    
 0.649
MUC4
Uncharacterized protein.
   
 0.629
TRIM77
Tripartite motif containing 77.
    
 0.580
UNC79
Unc-79 homolog, NALCN channel complex subunit.
   
 0.572
AGR2
Uncharacterized protein.
   
 
 0.521
TP63
Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
   
 
 0.520
TGM1
Transglutaminase 1.
   
 0.519
SERPINB12
Serpin family B member 12; Belongs to the serpin family.
   
 0.512
TGM3
TGc domain-containing protein.
   
 0.508
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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