SUPT16H protein (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC73	CTR9	ENSMMUP00000072840	ENSMMUP00000015006	Parafibromin.	CTR9 homolog, Paf1/RNA polymerase II complex component.	0.999
CDC73	LEO1	ENSMMUP00000072840	ENSMMUP00000003141	Parafibromin.	RNA polymerase-associated protein LEO1.	0.999
CDC73	POLR2A	ENSMMUP00000072840	ENSMMUP00000060307	Parafibromin.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.883
CDC73	POLR2B	ENSMMUP00000072840	ENSMMUP00000018410	Parafibromin.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.837
CDC73	POLR2C	ENSMMUP00000072840	ENSMMUP00000074354	Parafibromin.	RNA polymerase II subunit C.	0.792
CDC73	SSRP1	ENSMMUP00000072840	ENSMMUP00000072963	Parafibromin.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.928
CDC73	SUPT16H	ENSMMUP00000072840	ENSMMUP00000019664	Parafibromin.	SPT16 homolog, facilitates chromatin remodeling subunit.	0.934
CDC73	SUPT4H1	ENSMMUP00000072840	ENSMMUP00000047646	Parafibromin.	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	0.881
CDC73	SUPT5H	ENSMMUP00000072840	ENSMMUP00000031616	Parafibromin.	Transcription elongation factor SPT5.	0.885
CDC73	SUPT6H	ENSMMUP00000072840	ENSMMUP00000006255	Parafibromin.	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.	0.869
CTR9	CDC73	ENSMMUP00000015006	ENSMMUP00000072840	CTR9 homolog, Paf1/RNA polymerase II complex component.	Parafibromin.	0.999
CTR9	LEO1	ENSMMUP00000015006	ENSMMUP00000003141	CTR9 homolog, Paf1/RNA polymerase II complex component.	RNA polymerase-associated protein LEO1.	0.999
CTR9	POLR2A	ENSMMUP00000015006	ENSMMUP00000060307	CTR9 homolog, Paf1/RNA polymerase II complex component.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.888
CTR9	POLR2B	ENSMMUP00000015006	ENSMMUP00000018410	CTR9 homolog, Paf1/RNA polymerase II complex component.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.698
CTR9	POLR2C	ENSMMUP00000015006	ENSMMUP00000074354	CTR9 homolog, Paf1/RNA polymerase II complex component.	RNA polymerase II subunit C.	0.840
CTR9	SSRP1	ENSMMUP00000015006	ENSMMUP00000072963	CTR9 homolog, Paf1/RNA polymerase II complex component.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.948
CTR9	SUPT16H	ENSMMUP00000015006	ENSMMUP00000019664	CTR9 homolog, Paf1/RNA polymerase II complex component.	SPT16 homolog, facilitates chromatin remodeling subunit.	0.944
CTR9	SUPT4H1	ENSMMUP00000015006	ENSMMUP00000047646	CTR9 homolog, Paf1/RNA polymerase II complex component.	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	0.871
CTR9	SUPT5H	ENSMMUP00000015006	ENSMMUP00000031616	CTR9 homolog, Paf1/RNA polymerase II complex component.	Transcription elongation factor SPT5.	0.887
CTR9	SUPT6H	ENSMMUP00000015006	ENSMMUP00000006255	CTR9 homolog, Paf1/RNA polymerase II complex component.	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.	0.910