Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ARHGAP25Rho GTPase-activating protein 25 isoform a. (646 aa)    
Predicted Functional Partners:
WAS
WASP actin nucleation promoting factor.
   
   0.610
HCLS1
SH3 domain-containing protein.
   
    0.580
STK32A
Serine/threonine kinase 32A; Belongs to the protein kinase superfamily.
      
 0.527
PLD5
Phospholipase D family member 5.
   
  
 0.522
MTRF1L
Mitochondrial translational release factor 1 like.
      
 0.490
TRPC4AP
Transient receptor potential cation channel subfamily C member 4 associated protein.
      
 0.490
DENND1A
DENN domain containing 1A.
   
  
 0.467
TBL3
Transducin beta like 3.
    
   0.463
LSP1
Lymphocyte specific protein 1.
   
  
 0.448
SALL2
Spalt like transcription factor 2.
      
 0.438
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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