node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GRK5 | TAAR1 | ENSMMUP00000072367 | ENSMMUP00000019771 | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. | Trace amine-associated receptor 1; Receptor for trace amines, including beta-phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonin. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained spe [...] | 0.426 |
INMT | MAOA | ENSMMUP00000067770 | ENSMMUP00000025612 | Uncharacterized protein. | Amine oxidase. | 0.959 |
INMT | MAOB | ENSMMUP00000067770 | ENSMMUP00000069352 | Uncharacterized protein. | Amine oxidase. | 0.945 |
INMT | TAAR1 | ENSMMUP00000067770 | ENSMMUP00000019771 | Uncharacterized protein. | Trace amine-associated receptor 1; Receptor for trace amines, including beta-phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonin. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained spe [...] | 0.425 |
MAOA | INMT | ENSMMUP00000025612 | ENSMMUP00000067770 | Amine oxidase. | Uncharacterized protein. | 0.959 |
MAOA | MAOB | ENSMMUP00000025612 | ENSMMUP00000069352 | Amine oxidase. | Amine oxidase. | 0.927 |
MAOA | SLC6A4 | ENSMMUP00000025612 | ENSMMUP00000004679 | Amine oxidase. | Sodium-dependent serotonin transporter; Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily. | 0.898 |
MAOA | TAAR1 | ENSMMUP00000025612 | ENSMMUP00000019771 | Amine oxidase. | Trace amine-associated receptor 1; Receptor for trace amines, including beta-phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonin. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained spe [...] | 0.416 |
MAOB | INMT | ENSMMUP00000069352 | ENSMMUP00000067770 | Amine oxidase. | Uncharacterized protein. | 0.945 |
MAOB | MAOA | ENSMMUP00000069352 | ENSMMUP00000025612 | Amine oxidase. | Amine oxidase. | 0.927 |
MAOB | SLC6A4 | ENSMMUP00000069352 | ENSMMUP00000004679 | Amine oxidase. | Sodium-dependent serotonin transporter; Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily. | 0.798 |
MAOB | TAAR1 | ENSMMUP00000069352 | ENSMMUP00000019771 | Amine oxidase. | Trace amine-associated receptor 1; Receptor for trace amines, including beta-phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonin. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained spe [...] | 0.416 |
NLE1 | TAAR1 | ENSMMUP00000053946 | ENSMMUP00000019771 | Notchless protein homolog 1 isoform a. | Trace amine-associated receptor 1; Receptor for trace amines, including beta-phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonin. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained spe [...] | 0.609 |
PRKACA | PRKACB | ENSMMUP00000054168 | ENSMMUP00000059748 | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. | cAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. | 0.944 |
PRKACA | PRKACG | ENSMMUP00000054168 | ENSMMUP00000026815 | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. | cAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. | 0.900 |
PRKACA | TAAR1 | ENSMMUP00000054168 | ENSMMUP00000019771 | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. | Trace amine-associated receptor 1; Receptor for trace amines, including beta-phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonin. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained spe [...] | 0.540 |
PRKACB | PRKACA | ENSMMUP00000059748 | ENSMMUP00000054168 | cAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. | 0.944 |
PRKACB | PRKACG | ENSMMUP00000059748 | ENSMMUP00000026815 | cAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. | cAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. | 0.944 |
PRKACB | TAAR1 | ENSMMUP00000059748 | ENSMMUP00000019771 | cAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. | Trace amine-associated receptor 1; Receptor for trace amines, including beta-phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonin. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained spe [...] | 0.514 |
PRKACG | PRKACA | ENSMMUP00000026815 | ENSMMUP00000054168 | cAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. | 0.900 |