STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHISA8Shisa family member 8. (398 aa)    
Predicted Functional Partners:
POU3F4
POU domain protein.
      
 0.841
MEOX1
Mesenchyme homeobox 1.
      
 0.788
EYA1
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
      
 0.703
SHISA9
Shisa family member 9.
     
0.597
LDLRAD1
Low density lipoprotein receptor class A domain containing 1.
      
 0.591
GRIN1
Glutamate ionotropic receptor NMDA type subunit 1.
   
 
  0.574
SNTN
Sentan, cilia apical structure protein.
      
 0.574
SHISA7
Shisa family member 7.
  
  
0.571
CACNG8
Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
     
 0.555
GRIA1
Uncharacterized protein.
   
 
 0.546
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.