Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ANKRD54Ankyrin repeat domain-containing protein 54. (299 aa)    
Predicted Functional Partners:
TEAD4
TUB like protein 3; Belongs to the TUB family.
    
   0.902
BTK
Tyrosine-protein kinase.
    
 0.620
SH3YL1
SH3 and SYLF domain containing 1.
    
 
 0.611
BLOC1S6
Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...]
    
 0.585
ARHGAP26
Rho GTPase activating protein 26.
    
 
 0.530
DLG3
Uncharacterized protein; Belongs to the MAGUK family.
    
 0.519
LIAS
Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
      
 0.516
BLK
Tyrosine-protein kinase.
    
 0.508
ASB13
Ankyrin repeat and SOCS box containing 13.
  
     0.498
ITK
Tyrosine-protein kinase.
    
 0.498
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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