Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PTS6-pyruvoyltetrahydropterin synthase. (216 aa)    
Predicted Functional Partners:
GCH1
GTP cyclohydrolase 1.
  
 
 0.995
SPR
Sepiapterin reductase.
  
 
 0.995
GCHFR
GTP cyclohydrolase I feedback regulator.
     
 0.904
AKR1B1
Aldo_ket_red domain-containing protein.
    
 0.903
AKR1B10
Aldo-keto reductase family 1 member B10.
    
 0.902
AKR1C1
Aldo_ket_red domain-containing protein.
    
 0.902
AKR1C8P
Aldo-keto reductase family 1 member C8, pseudogene.
    
 0.902
LOC722496
Aldo_ket_red domain-containing protein.
    
 0.902
ALPP
Alkaline phosphatase.
     
  0.900
ALPI
Alkaline phosphatase.
     
  0.900
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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