STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRSS12Neurotrypsin; Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations; Belongs to the peptidase S1 family. (875 aa)    
Predicted Functional Partners:
AGRN
Agrin.
   
 0.666
KCNH4
Potassium voltage-gated channel subfamily H member 4.
      
 0.651
GAMT
RMT2 domain-containing protein.
      
 0.582
SCN4B
Sodium voltage-gated channel beta subunit 4.
      
 0.579
BOP1
Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
      
 0.552
COL24A1
Collagen type XXIV alpha 1 chain.
    
 0.549
BBS1
Dipeptidyl peptidase 3; Belongs to the peptidase M49 family.
   
  
 0.547
L1CAM
Uncharacterized protein.
    
 0.519
TPBG
Uncharacterized protein.
    
 0.514
CC2D1A
Coiled-coil and C2 domain containing 1A.
      
 0.507
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.