Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CPSF7Cleavage and polyadenylation specific factor 7. (471 aa)    
Predicted Functional Partners:
CPSF6
Cleavage and polyadenylation specific factor 6.
  
0.999
NUDT21
Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]
   
 0.996
CPSF2
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.995
CPSF3
Cleavage and polyadenylation specificity factor subunit 3.
   
 0.991
CSTF2T
Cleavage stimulation factor subunit 2 tau variant.
   
 0.987
CPSF4
Cleavage and polyadenylation specific factor 4.
   
 0.983
PCF11
PCF11 cleavage and polyadenylation factor subunit.
    
 0.975
SYMPK
Symplekin.
   
 0.973
WDR33
WD repeat domain 33.
   
 0.963
CPSF4L
Cleavage and polyadenylation specific factor 4 like.
   
 0.957
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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