ABCA7 protein (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ABCA7

ATP binding cassette subfamily A member 7. (2111 aa)

Predicted Functional Partners:

PICALM

0.827

APOA1

0.826

CD2AP

0.810

BIN1

0.792

EPHA1

0.784

CLU

0.761

CD33

0.750

TREM2

0.708

SORL1

0.705

MS4A6A

0.663

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA7	APOA1	ENSMMUP00000020070	ENSMMUP00000021209	ATP binding cassette subfamily A member 7.	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.	0.826
ABCA7	BIN1	ENSMMUP00000020070	ENSMMUP00000053644	ATP binding cassette subfamily A member 7.	Bridging integrator 1.	0.792
ABCA7	CD2AP	ENSMMUP00000020070	ENSMMUP00000065198	ATP binding cassette subfamily A member 7.	CD2-associated protein.	0.810
ABCA7	CD33	ENSMMUP00000020070	ENSMMUP00000046076	ATP binding cassette subfamily A member 7.	CD33 molecule.	0.750
ABCA7	CLU	ENSMMUP00000020070	ENSMMUP00000069256	ATP binding cassette subfamily A member 7.	Clusterin; Belongs to the clusterin family.	0.761
ABCA7	EPHA1	ENSMMUP00000020070	ENSMMUP00000078550	ATP binding cassette subfamily A member 7.	EPH receptor A1.	0.784
ABCA7	MS4A6A	ENSMMUP00000020070	ENSMMUP00000017792	ATP binding cassette subfamily A member 7.	Membrane spanning 4-domains A6A.	0.663
ABCA7	PICALM	ENSMMUP00000020070	ENSMMUP00000025765	ATP binding cassette subfamily A member 7.	Phosphatidylinositol binding clathrin assembly protein.	0.827
ABCA7	SORL1	ENSMMUP00000020070	ENSMMUP00000053778	ATP binding cassette subfamily A member 7.	Sortilin related receptor 1.	0.705
ABCA7	TREM2	ENSMMUP00000020070	ENSMMUP00000033713	ATP binding cassette subfamily A member 7.	Triggering receptor expressed on myeloid cells 2.	0.708
APOA1	ABCA7	ENSMMUP00000021209	ENSMMUP00000020070	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.	ATP binding cassette subfamily A member 7.	0.826
APOA1	CLU	ENSMMUP00000021209	ENSMMUP00000069256	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.	Clusterin; Belongs to the clusterin family.	0.813
APOA1	TREM2	ENSMMUP00000021209	ENSMMUP00000033713	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.	Triggering receptor expressed on myeloid cells 2.	0.472
BIN1	ABCA7	ENSMMUP00000053644	ENSMMUP00000020070	Bridging integrator 1.	ATP binding cassette subfamily A member 7.	0.792
BIN1	CD2AP	ENSMMUP00000053644	ENSMMUP00000065198	Bridging integrator 1.	CD2-associated protein.	0.780
BIN1	CD33	ENSMMUP00000053644	ENSMMUP00000046076	Bridging integrator 1.	CD33 molecule.	0.704
BIN1	CLU	ENSMMUP00000053644	ENSMMUP00000069256	Bridging integrator 1.	Clusterin; Belongs to the clusterin family.	0.884
BIN1	EPHA1	ENSMMUP00000053644	ENSMMUP00000078550	Bridging integrator 1.	EPH receptor A1.	0.747
BIN1	MS4A6A	ENSMMUP00000053644	ENSMMUP00000017792	Bridging integrator 1.	Membrane spanning 4-domains A6A.	0.624
BIN1	PICALM	ENSMMUP00000053644	ENSMMUP00000025765	Bridging integrator 1.	Phosphatidylinositol binding clathrin assembly protein.	0.877