STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCNQ5Potassium voltage-gated channel subfamily Q member 5. (951 aa)    
Predicted Functional Partners:
KCNQ2
Potassium voltage-gated channel subfamily Q member 2.
  
  
0.974
KCNQ3
Potassium voltage-gated channel subfamily KQT member 3 isoform 1; Belongs to the potassium channel family.
  
 
0.972
KCNQ1
Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.
  
0.967
KCNQ4
Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family.
  
  
0.952
KCNJ2
Inward rectifier potassium channel 2; Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be bl [...]
   
 
 0.934
KCNJ4
Potassium voltage-gated channel subfamily J member 4.
   
 
 0.915
KCNJ12
Uncharacterized protein.
   
 
 0.914
KCNJ14
Potassium voltage-gated channel subfamily J member 14.
   
 
 0.911
FAU
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.896
NR3C2
Nuclear receptor subfamily 3 group C member 2.
      
 0.751
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.