Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SLKSTE20 like kinase. (1236 aa)    
Predicted Functional Partners:
PLK1
Serine/threonine-protein kinase PLK.
    
0.909
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
     
 
0.900
CCNB2
Cyclin B2; Belongs to the cyclin family.
     
  0.900
RPL37A
Uncharacterized protein.
    
   0.740
KEAP1
Kelch like ECH associated protein 1.
    
   0.674
YWHAB
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family.
    
   0.669
RHOA
Ras homolog family member A.
    
 0.657
RDX
Radixin.
   
 
 0.624
MSN
FERM domain-containing protein.
    
 
 0.619
EZR
Ezrin.
    
 
 0.600
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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