Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RSPO3R-spondin 3. (273 aa)    
Predicted Functional Partners:
LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4.
   
 0.992
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
   
 0.992
RNF43
RING-type domain-containing protein.
    
 0.979
ZNRF3
Zinc and ring finger 3.
    
 0.965
LGR6
Leucine rich repeat containing G protein-coupled receptor 6.
    
 0.960
RSPO1
R-spondin 1.
  
  
0.959
RSPO2
Uncharacterized protein.
  
  
0.943
WNT9B
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
      
 0.665
WNT2B
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
   
  
 0.651
CTNNB1
Catenin beta-1.
   
 0.589
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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