Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLXDC2Plexin domain containing 2. (529 aa)    
Predicted Functional Partners:
KLHL25
BTB domain-containing protein.
      
 0.790
SLC22A3
Solute carrier family 22 member 3.
      
 0.576
HEXA
Beta-hexosaminidase.
      
 0.575
HS6ST3
Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
      
 0.570
MYSM1
Myb like, SWIRM and MPN domains 1.
      
 0.525
LPCAT2
Lysophosphatidylcholine acyltransferase 2.
      
 0.525
HEXB
Beta-hexosaminidase.
      
 0.525
STARD13
Uncharacterized protein.
      
 0.518
FMN1
Formin 1.
      
 0.492
ZP4
Zona pellucida glycoprotein 4.
      
 0.492
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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